26
3
25
Cat. No. | Product Name | Target | Signaling Pathways |
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T65148 |
Estradiene dione-3-keta
|
||
Estradiene dione-3-keta 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65148,CAS号为 5571-36-8。 | |||
T66298 | (8S,9S,10R,14S)-13-Ethyl-11-methylene-2,3,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(6H)-one | ||
(8S,9S,10R,14S)-13-Ethyl-11-methylene-2,3,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(6H)-one 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66298,CAS号为 54024-21-4。 | |||
T66315 | (7R,8R,9S,13S,14S,17S)-7-(9-Bromononyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol | ||
(7R,8R,9S,13S,14S,17S)-7-(9-Bromononyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66315,CAS号为 875573-67-4。 | |||
T66301 | (3S,8R,9S,10R,13S,14S)-17-Iodo-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol | ||
(3S,8R,9S,10R,13S,14S)-17-Iodo-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66301,CAS号为 32138-69-5。 | |||
T64564 |
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37-dodecaoxa-4-azatetracontan-40-oic acid
|
||
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37-dodecaoxa-4-azatetracontan-40-oic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64564。 | |||
T65404 | (2'R,7R,8R,10S,13S,14S)-Methyl 10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,10,12,13,14,15,16-tetradecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-carboxylate | ||
(2'R,7R,8R,10S,13S,14S)-Methyl 10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,10,12,13,14,15,16-tetradecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-carboxylate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65404,CAS号为 95716-70-4。 | |||
T65421 | Rifamycin O | ||
Rifamycin O 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65421,CAS号为 14487-05-9。 | |||
T65075 |
(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate
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(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65075,CAS号为 17110-51-9。 | |||
T66656 |
(R)-Methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
|
||
(R)-Methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66656,CAS号为 10538-59-7。 | |||
T66748 | (R)-Methyl 4-((3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate | ||
(R)-Methyl 4-((3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66748,CAS号为 2868-48-6。 | |||
T66990 | (R)-Benzyl 4-((3R,5R,8S,9S,10R,13R,14S,17R,E)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate | ||
(R)-Benzyl 4-((3R,5R,8S,9S,10R,13R,14S,17R,E)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66990,CAS号为 1352328-66-5。 | |||
T66136 | (R)-Methyl 4-((3R,5S,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate | ||
(R)-Methyl 4-((3R,5S,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66136,CAS号为 10538-65-5。 | |||
T66741 |
(R)-4-((3R,5R,8S,9S,10R,13R,14S,17R,E)-6-Ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
|
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(R)-4-((3R,5R,8S,9S,10R,13R,14S,17R,E)-6-Ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66741,CAS号为 1516887-33-4。 | |||
T64669 |
(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-7,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
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(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-7,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64669。 | |||
T64990 |
(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-Dimethyl-2,16-di(piperidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
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(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-Dimethyl-2,16-di(piperidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64990,CAS号为 13522-16-2。 | |||
T1876 |
Kobe0065
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Apoptosis; Raf; Ras | Apoptosis; GPCR/G Protein; MAPK |
Kobe0065 是一种新型 Ras-Raf 相互作用抑制剂,可完全抑制 H-Ras·GTP 与 c-Raf-1 RBD 的结合,Ki 值为 46±13 μM。 | |||
T22831 |
Protein kinase inhibitor H-7 dihydrochloride
H-7 dihydrochloride |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride0) 是一种有效的蛋白激酶 C(PKC)抑制剂。Protein kinase inhibitor H-7 dihydrochloride(100 μM)显著抑制 TPA (皮肤肿瘤启动子,12-O-tetradecanoylphorbol-13-acetate) 和磷脂酶 C 促使的 ODC (鸟氨酸脱羧酶),抑制 PMA 诱导的混杂细胞溶解活性。 | |||
T14943 |
CGP60474
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VEGFR; CDK; PKC | Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
CGP60474 是一种高效的抗内毒素药物,抑制细胞周期蛋白依赖激酶(CDK) ,抑制 CDK1/B、CDK2/E、CDK2/a、CDK4/D、CDK5/p25、CDK7/H 和 CDK9/T 的IC50分别为 26、3、4、216、10、200 和 13 nM。它是选择性和 ATP 竞争性PKC 抑制剂。 | |||
T35610 |
2,5-dimethyl Celecoxib
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Apoptosis; Wnt/beta-catenin; Prostaglandin Receptor | Apoptosis; Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Stem Cells |
2,5-dimethyl Celecoxib 是塞来昔布衍生物和微粒体前列腺素 E 合酶 1 (mPGES-1) 的靶向抑制剂,mPGES-1 是炎症介质 PGE2 合成途径中的关键酶。 | |||
T25481 |
H 77
H77,H-77 |
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H 77 is a new effective renin inhibitor. H 77 is angiotensinogen (6-13)-octapeptide in which the peptide bond -CO-NH- at the Leu(9)-Leu(11) linkage is replaced by a -CH2-NH- bond. | |||
T37447 |
UZH1
UZH1 |
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UZH1 is a racemate of UZH1a and UZH1b. UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1b (IC50=28 μM) is essentially inactive. UZH1 can be used for epitranscriptomic modulation of cellular processes. UZH1 has antitumor activity. UZH1 also can be used as a chemical probe for studying METTL3[1]. UZH1a (2.5-160 μM; 72 h) inhibits the growth of MOLM-13, HEK293T, and U2Os cells, with IC50s of 11 μM, 67 μM, and 87 μM, respectively[1].UZH1b (2.5-160 μM; 72 h) inhibits the ... | |||
T36412 |
Multiflorenol
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Multiflorenol is a triterpene that has been found in T. kirilowii seeds.1 It inhibits in vitro activation of Epstein-Barr virus early antigen (EBV-EA) induced by the tumor promoter phorbol 12-myristate 13-acetate in a concentration-dependent manner. |1. Akihisa, T., Tokuda, H., Ichiishi, E., et al. Anti-tumor promoting effects of multiflorane-type triterpenoids and cytotoxic activity of karounidiol against human cancer cell lines. Cancer Lett. 173(1), 9-14 (2001). | |||
T36916 |
Estrone-3-Glucuronide (sodium salt hydrate)
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Estrone-3-Glucuronide is a metabolite of the primary premenopausal estrogen 17β-estradiol .1,2Urinary levels of estrone-3-Glucuronide peak approximately 36 hours prior to ovulation and have been used as a marker of fertility in women. 1.Blackwell, L.F., Brown, J.B., and Cooke, D.Definition of the potentially fertile period from urinary steroid excretion rates. Part II. A threshold value for pregnanediol glucuronide as a marker for the end of the potentially fertile period in the human menstrual ... | |||
T35406 |
α-MSH TFA
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α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.1It is an agonist of melanocortin receptor 3 (MC3R) and MC4R that induces cAMP production in Hepa cells expressing the human receptors (EC50s = 0.16 and 56 nM, respectively).2α-MSH (100 pM) reducesS. aureuscolony formation andC. albicansgerm tube fo... | |||
T35698 |
Octanoic Acid-13C
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Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d... | |||
T35790 |
Palmitic acid-1,2,3,4-13C4
Palmitic Acid-13C (C1, C2, C3, and C4 labeled) |
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Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T21513 |
Cytochalasin H
(16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl) acetate,细胞松驰素 H |
MMP | Proteases/Proteasome |
Cytochalasin H ((16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl) acetate) 是肌动蛋白掺入细丝的有效抑制剂。 | |||
T79954 |
Kadsulignan H
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NO Synthase | Immunology/Inflammation |
Kadsulignan H (compound 13),作为一种木脂素类化合物,展现了对 NO 产生的显著抑制作用。在 BV-2 细胞中,该化合物通过 IC50 值为 14.1 μM 来表征其对 NO 生成的抑制活性。 | |||
TN4140 |
Glochidiol
|
Others | Others |
Glochidiol exhibits strong inhibitory effects against all three human tumor cell lines (MCF-7, NCI-H-460 and SF-268), it exerts its antiproliferative activity through the involvement of apoptosis. It exhibits a strong inhibitory effect on mouse skin tumor |
Cat. No. | Product Name | Species | Expression System |
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TMPY-02580 |
Histone H1 Protein, Human, Recombinant (His)
HSP60,HSP65,CPN60,H1 his... |
Human | E. coli |
H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes, all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-termin... | |||
TMPJ-00483 |
DFF45 Protein, Human, Recombinant (His)
DNA Fragmentation Factor Subunit Alpha,DFF45,H<... |
Human | E. coli |
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression. | |||
TMPY-05933 |
Influenza A H1N1 (A/Arizona/13/2008) Neuraminidase/NA (His)
NA Protein |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Arizona/13/2008) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is B9W3K0. | |||
TMPY-01513 |
Influenza A H1N2 (A/swine/Guangxi/13/2006) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N2 | HEK293 Cells |
Influenza A H1N2 (A/swine/Guangxi/13/2006) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is A5JQC7. | |||
TMPY-06025 |
Influenza A H1N1 (A/swine/Henan/SN13/2018) Neuraminidase/NA Protein (His)
NA Protein |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/swine/Henan/SN13/2018) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is A0A6G5UYS3. | |||
TMPY-05847 |
Influenza A H1N1 (A/swine/Henan/SN13/2018) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/swine/Henan/SN13/2018) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.07 kDa and the accession number is A0A6G5UYK1. | |||
TMPY-01514 |
Influenza A H1N2 (A/swine/Guangxi/13/2006) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N2 | HEK293 Cells |
Influenza A H1N2 (A/swine/Guangxi/13/2006) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is A5JQC7. | |||
TMPY-05897 |
Influenza A H3N2 (A/swine/Mexico/AVX13/2012) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/swine/Mexico/AVX13/2012) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.8 kDa and the accession number is A0A165EUH9. | |||
TMPY-00267 |
Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H13N6 | Baculovirus Insect Cells |
Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q5DL25. | |||
TMPY-00079 |
Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H13N8 | Baculovirus Insect Cells |
Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is Q5DL26. | |||
TMPY-01623 |
Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H13N8 | HEK293 Cells |
Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.4 kDa and the accession number is Q5DL26. | |||
TMPY-04862 |
Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H13N6 | HEK293 Cells |
Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q5DL25. | |||
TMPY-06426 |
SARS-CoV-2 Nucleocapsid Protein (P13L & R203K & G204R & Q384H, His)
|
SARS-CoV-2 | E. coli |
SARS-CoV-2 Nucleocapsid Protein (P13L & R203K & G204R & Q384H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.69 kDa and the accession number is P0DTC9. | |||
TMPY-03798 |
H Cadherin Protein, Rat, Recombinant (His)
cadherin 13 |
Rat | HEK293 Cells |
CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer. H Cadheri... | |||
TMPY-03948 |
H Cadherin Protein, Rat, Recombinant
cadherin 13 |
Rat | HEK293 Cells |
CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer. H Cadheri... | |||
TMPY-00601 |
H Cadherin Protein, Mouse, Recombinant (hFc)
Tcad,T-cadherin,4932416G01Rik,cadherin |
Mouse | HEK293 Cells |
CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer. H Cadheri... | |||
TMPY-03823 |
H Cadherin Protein, Rat, Recombinant (hFc)
cadherin 13 |
Rat | HEK293 Cells |
CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer. H Cadheri... | |||
TMPY-00450 |
H Cadherin Protein, Mouse, Recombinant (His)
Cdht,T-cadherin,cadherin 13 |
Mouse | HEK293 Cells |
CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer. H Cadheri... | |||
TMPK-01373 |
Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc)
FINC,LETS,GFND,SMDCF,GFND2,ED-B,MSF,FNZ,FN1,FN,CIG |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicte... | |||
TMPK-01391 |
Fibronectin Protein, Human, Recombinant (aa 1266-1356, His)
FN1,LETS,GFND,MSF,FNZ,CIG,ED-B,FN,SMDCF,GFND2,FINC |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 1266-1356, His) is expressed in HEK293 mammalian cells with C-His tag. The predicte... | |||
TMPK-01413 |
H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
H-2K,OVA,MHC,H2-K1 |
Mouse | HEK293 Cells |
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se... | |||
TMPK-01523 |
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)
WAGR,WT33,AWT1,GUD,RMF,WT1,WIT-2,MHC,NPHS4... |
Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1. | |||
TMPK-01534 |
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)
RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,M |
Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
TMPK-01522 |
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4... |
Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1. | |||
TMPK-01535 |
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Macropain chain 7,LMP2,Proteasome chain 7,... |
Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... |